Non-psychotropic constituent of cannabis that is anticonvulsive, antihyperalgesic and neuroprotective in vivo. GPR55 and weak CB1 antagonist (IC50 values are 0.445 and 3.35 μ M), CB2 receptor inverse agonist and inhibitor of anandamide uptake (IC50 = 27.5 μ M). Also inhibits FABPs and a weak agonist at TRP vanilloid receptors (EC50 = 3.5 μ M).
|Storage||Store at -20°C|
|Smiles||CCCCCC1=CC(O)=C([[email protected]]2C=C(C)CC[[email protected]]2C(C)=C)C(O)=C1|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 314.47 . Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
View and buy high purity (-)-Cannabidiol from Tocris Bioscience. Natural cannabinoid; GPR55 antagonist, weak CB1 antagonist, CB2 inverse agonist and AMT inhibitor. Cited in 5 publications.